Researchers have developed a new technology that helps Parkinson's patients overcome the tendency to speak too quietly by playing a recording of ambient sound, which resembles the noisy chatter of a restaurant full of patrons.
WEST LAFAYETTE, Ind.--(BUSINESS WIRE)--Researchers have developed a new technology that helps Parkinson's patients overcome the tendency to speak too quietly by playing a recording of ambient sound, which resembles the noisy chatter of a restaurant full of patrons.
"People with Parkinson's disease commonly have voice and speech problems," said Jessica Huber, an associate professor in Purdue's Department of Speech, Language and Hearing Sciences. "At some point in their disease they will have some form of voice or speech disorder that generally occurs a little later in the disease."
Parkinson's affects 1.5 million people in the United States and is one of the most common degenerative neurological diseases. About 89 percent of those with Parkinson's have voice-related change, which is related to how loudly they speak, and about 45 percent have speech-related change, or how clearly they speak.
"A major therapy is to get people to speak louder, which also may cause them to articulate more clearly," Huber said.
The most common therapy, the Lee Silverman voice treatment program, trains patients to speak louder in one-hour sessions four days a week for a month.
"Some Parkinson's patients do great with this approach, but others do not," Huber said. "They forget to keep speaking louder the minute they have left the therapy room. Lee Silverman tends to work less for people with later stages of disease or those who have some cognitive decline. So I wanted to know whether there was an easier way to cue people during therapy, rather than telling them, 'Try to be twice as loud,' or 'Try to focus on this sound meter and achieve this loudness.'"
Huber used a new approach: Patients were asked to speak louder while a recording of background "multitalker babble noise" was played. The noise is essentially the sound of a restaurant full of patrons, but without clattering silverware and clinking glasses.
The background sound elicits a well-known phenomenon called the Lombard effect, a reflex in which people automatically speak louder in the presence of background sound.
"You go into a loud room at a party and you talk louder without even realizing it," Huber said. "We've all had the experience where the room suddenly gets quiet and you're still shouting but you didn't know you were."
Huber created a new electronic technology using this principle. The voice-activated device automatically plays the background babble when the person begins to speak.
A critical part of the research is to integrate the voice-detection sensor, called an accelerometer, developed in work led by biomedical engineering doctoral students Matias Zanartu and Julio C. Ho and biomedical engineering professor George Wodicka, head of Purdue's Weldon School of Biomedical Engineering.
"This sensor is crucial because it is essential that the background babble noise only turn on when the subject talks," Huber said.
The device prototype was built by engineering resources manager Jim Jones and senior research engineer Kirk Foster, both in the Weldon School. An earlier prototype had been built by Scott Kepner, manager of technical services, and Derek Tully, assistant manager of technical services, both in the Department of Speech, Language and Hearing Sciences.
Six patients wore the portable system for eight weeks. Data collected showed the system effectively prompts Parkinson's patients to speak louder and more clearly.
"Their speech changes significantly," said Huber, who is working with Meghan Darling, a doctoral student in Speech, Language and Hearing Sciences. "There have been times where I have called patients and they've had the device on and I didn't really recognize them. And these are patients I've known for a long time."
Researchers will work in the future with patients at the Rehabilitation Institute of Indianapolis.
The research is funded by the National Institutes of Health. Purdue Research Foundation's Office of Technology Commercialization has filed a provisional patent on the concept.
The researchers are seeking Parkinson's disease patients to participate in the study. To participate, or for more information on the study, contact Huber at 765-494-3796, jhuber@purdue.edu.
